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Persistent hyperplastic primary vitreous : ウィキペディア英語版 | Persistent hyperplastic primary vitreous
Persistent hyperplastic primary vitreous (PHPV), also known as Persistent Fetal Vasculature (PFV), is a rare congenital developmental anomaly of the eye that results following failure of the embryological, primary vitreous and hyaloid vasculature to regress. It can be present in three forms: purely anterior (persistent tunica vasculosa lentis and persistent posterior fetal fibrovascular sheath of the lens), purely posterior (falciform retinal septum and ablatio falcicormis congenita) and a combination of both.〔 Most examples of PHPV are unilateral and non-hereditary. When bilateral, PHPV may follow an autosomal recessive or autosomal dominant inheritance pattern. ==Causes/association of bilateral PHPV== #Trisomy 13 (Patau syndrome) #Norrie disease #Walker-Warburg syndrome #Autosomal dominant #Autosomal recessive
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